Director of Modelling (Biotechnology, Copenhagen/Remote)

Job summary

The role involves leading mechanistic and translational PK/PD modelling to support model-informed drug development (MIDD) in metabolic health, focusing on preclinical and early clinical programs. The position requires collaboration with various scientific teams to integrate quantitative modelling into project strategies.

Qualifications

• PhD in pharmacometrics, PK/PD modelling, or a related quantitative field with significant industry experience.
• Proven experience in translational and mechanistic PK/PD modelling that influences early clinical development decisions.
• Strong background in MATLAB/SimBiology, PBPK software, and population PK/PD tools (e.g., NONMEM, Phoenix).

Responsibilities

• Lead hands-on mechanistic and translational PK/PD modelling to enable MIDD from preclinical to early clinical development.
• Develop mechanistic and semi-mechanistic models to support dose selection and study design.
• Translate preclinical data into quantitative predictions for early clinical studies.
• Manage collaborations with external partners, ensuring high-quality modelling outputs.
• Contribute to internal governance and regulatory documentation related to MIDD.

Skills

• Strong communication and stakeholder management skills.
• Ability to translate complex quantitative work into clear insights.
• Experience in writing regulatory documents and communicating scientific assumptions.

Education

• PhD in a relevant quantitative discipline.

Tools

• MATLAB/SimBiology, PBPK software, R, and population PK/PD tools.