Staff Scientist in Organoid Biology (Biotechnology, Remote)

Job summary

A highly motivated and experienced Staff Scientist is sought to lead a groundbreaking initiative focused on RNA therapeutics for cardiometabolic diseases. This role involves contributing to the translation of basic disease findings into medicinal RNA approaches, with a commitment to improving patient outcomes.

Qualifications

• PhD in molecular biology, biochemistry, cell biology, physiology, or a related field with strong methodological focus.
• Several years of postdoctoral or equivalent experience, evidenced by high-impact publications and patents.
• Proven ability to train and mentor researchers.
• Strong collaboration and problem-solving skills, with the ability to work independently and in teams.
• Excellent written and verbal communication skills, with a passion for therapeutic translation.
• Meticulous and organized, capable of managing complex projects and maintaining high-quality documentation.

Responsibilities

• Establishing, validating, and maintaining human adipose organoid platforms.
• Testing LNP-mRNA and antisense oligonucleotides to target human micro/mRNA.
• Upscaling human adipose and liver organotypic setups to robotic systems.
• Writing and implementing standard operating procedures (SOPs) and managing critical instruments.
• Providing hands-on training and guidance to PhD students, postdocs, and technical staff.
• Leading collaborative projects, designing experiments, troubleshooting issues, and generating high-quality data.

Skills

• Expertise in iPSC models focusing on adipocytes/adipose tissue.
• Experience with RNA-based platforms in cardiometabolic cells and tissues.
• Proficiency in designing and benchmarking anti-miRs and microRNA AAV decoys.
• Familiarity with rodent models of metabolic disease and animal husbandry.

Education

• PhD in a relevant scientific field.

Tools

• Experience with proteomics, molecular biology techniques, and in vivo studies.